Dr. Fiocchi obtained his medical degree from the Santa Casa Faculty of Medicine in São Paulo, Brazil, followed by training in internal medicine, immunology and gastroenterology in São Paulo, Baltimore, and Cleveland. Currently Dr. Fiocchi is Professor of Molecular Medicine at the Cleveland Clinic Lerner College of Medicine, Cleveland, and a staff member of the Department of Inflammation & Immunity in the Lerner Research Institute of the Cleveland Clinic.
His lifelong research interest is the pathogenesis of inflammatory bowel disease (IBD), where he has made numerous contributions. These included the investigation of immune events occurring in the bowel of Crohn’s disease and ulcerative colitis patients, as well as animal models of IBD. The studies included the identification of mechanisms of mucosal T-cell death and survival, investigation of tolerance of mucosal T-cells for the autologous enteric flora, characterization of the interactions between mucosal T-cells and endothelial and stromal cells, and the study of immune-driven angiogenesis in intestinal inflammation. His most recent area of interest is the use of systems biology and network medicine to understand IBD pathogenesis in a more comprehensive fashion.
Dr. Fiocchi has received numerous recognitions and awards as well as serving as Associate Editor or Editorial Board member of several journals.